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Undifferentiated Pleomorphic Sarcoma

Sarcoma | Last Active: 1 day ago | Replies (77)

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@jbbj

Hi,
My mother dignosis with UPS metastatic, she has pain in left hand, then left leg, after 2 month with many test & 4 biopsy result show result as UPS, unidentified primary sarcomatoid carcinoma.
1 chemo Paclitaxel-120 mg + Inj carboplatin 200mg further stopped as there was no CK biomarker positive.
10 radiotherapy Given on Left clavicle bone, L4, L5 Left Hemipelvis with 3DCRT technique on LINAC
to a total dose of 30Gy/10.
Futher 1 month pazopanib 400mg given but lot of side effects it was.
NGS sarcoma Panel-Negative, only gene SDHB-Biomarker positive.
Last hope & try for PEMBROLIZUMAB -200mg suggested.
Request for expert opnion review

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Replies to "Hi, My mother dignosis with UPS metastatic, she has pain in left hand, then left leg,..."

@jbbj, welcome to Mayo Clinic Connect, a place to meet other patients and family caregivers living with similar health issues.

It sounds, however, like you are looking for an expert review with Mayo Clinic specialists. To seek a second opinion at Mayo Clinic, you can start here: http://mayocl.in/1mtmR63

It must be so hard to see you mom dealing with the side effects of treatment. When will she start immunotherapy with Pembrolizumab? How are you doing?