Hi Frankie160,
I am so sorry to hear your MAC is back again!! It happens to most patients and please do not feel disappointed. I did not feel much fatigue from amikacin, but due to bleeding, I switched it from 7 times to 3 times. I also rinse my mouth when I used it, so my vocal cord does not change much. Now it is 3 times a week, and my voice is back to normal. Did you drink a lot of water? It hurts kidney and liver function so we need to stay hydrated.

Did you try Smart vest? Maye it can help with COPD and airway clearance? I just got it this week and feel good about it.

In addition, I always try to put on more weight as slender type is prone to bacterial infection and make us more sensitive to medicine side effects.

I hope you stay strong and stay well!!!