← Return to Letrozole joints, bone loss, low platelets, high cholesterol

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@flowergal

Exactly. I need to ask again what the percentage of a return is without AI.

Thank you for the reminder.

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Replies to "Exactly. I need to ask again what the percentage of a return is without AI. Thank..."

Hello flowergirl,
You may want to look at Exemestane as an alternative to the other AIs.
Was on both, same issues…these drugs are crippling. Ask your pharmacist what the 1/2 life is on all of them.
Exemestane is 50 hours. Perhaps after your being on it for 3 months, your onc will let you go every other day because of the half life.

I dont know if your drs discussed Faslodex, but its 2 shots on each cheeky.
If your cancer is attracted to estrogen, yes, youll need an AI or something like Falslodex.
However, if your cancer was not attracted to progesterone, you could actually use that to balance the estrogen.

Look for Dr. John Lees book on this.
Sadly he passed away years ago, but he actually reversed osteoporosis in his patients who had estrogen dominance.
HOWEVER, look into mushrooms as specific ones are excellent aromatase inhibitors. But youll have to consume a good quantity. Perhaps Exemestane one day, mushrooms the next.

You and me both!! Letrozole was a No Go for me..lots of joint pain and mood swings.
Now on Anastrozole, and was put on a 600 mg, 3x/day Motrin regime for 5 weeks…but my thumb pain drove me to the Ortho Surgeon. Got shots in both thumbs, and he said I’m a good candidate for thumb joint replacement (9-12 mo recovery) and painful. I want to just STOP AI’s!!! Going to dr Friday to talk about it. I’m 71 almost…life’s too short for these mood swings and 24/7 joint pain!