I have also experienced neuropathic itch……which can be severe and drive you crazy. When it’s bad I have purpura red spots on my arms, legs. I have found that many times it is caused by a new cream, pill that I’ve tried and when stopping them the severe itching lessens. Right now I don’t take anything but my usual vitamin supplements. However, when the itching starts I have to get right up and put body lotion on those areas and wait a few minutes…..it then starts to subside.