Jeffmarc,
Thanks so much for the information. So you have been taking 6 senna and four Colace pills a day, plus occasionally some MiraLAX, for a few years with, I assume, no negative effects. That it really helpful for me to hear. I guess I don't need to be so afraid of those higher doses damaging my colon. I discussed my constipation with my Radiation Oncologist before starting down this path and she made it clear she requires a clean colon to administer the radiation to the prostate. I'll ask her about the NCCN standard. Curiously, before my cardiologist cleared me for ADT, my RO told me I would be fine with no ADT, just radiation. She said ADT would accelerate my atherosclerosis. Once my cardiologist cleared me for ADT, ADT became necessary... Thanks again!