Thanks -- that's helpful.

Did he say what the additional predictive value was over rising PSA alone after a radical prostatectomy or major radiation?

I can see the value of a testing refinement after highly-focussed treatment like proton therapy or a focal ablation, when enough of the prostate still functions that rising PSA could be harmless, but if they've completely removed the prostate or fried it thoroughly a high dose of photon-based EBRT, then I'd think any rising PSA is automatically cause for concern (since we know it's not coming from the prostate), and the main value of adding epigenetic testing would be to confirm that epigenetic testing works.