ikhender, I hope this message gets to you. I'm replying to myself because I don't know how to reach someone if there is no recent post from them. In one of your posts, I think it was in September, you sent an article from the publication "Cureus" entitled "A Rare Presentation of Zoledronate-Induced Systemic Inflammatory Response." It's an excellent article about an 82 year old that had severe side effects from Reclast. I made a copy of the article, and refer back to it often. I tried to find your post that had the link with it, but couldn't find it. I wonder if you could post it again. I want everyone to see how the doctors helped this woman, and all the tests that are available to determine if the side effects are from the Relast. Several people seem to think that doctors cannot come up with a definitive diagnosis. The tools are there. Just have to find a doctor willing to use them.