PSE Test for Prostate Cancer Before an MRI and for Re-Occurrence

Posted by bens1 @bens1, Oct 22 8:31pm

I had a discussion with a SVP at Oxford Biodynamics last night about the accuracy of their PSE test for both potentially new prostate cancer patients and for those that get tested for biological re-occurrence. He basically explained, in layman’s terms, that regardless of having had treatment or not, the PSE tests 5 biomarkers will be accurate to show the likelihood or not, of prostate cancer 94% of the time.

He said that a change at the cellular level, because of new cancer cells, even when a psma pet scan will not pick up the micro cells, that their test will pick it up.

I have attached a chart he provided. Obviously part of his job is to spread the word, but I believe his intent to help was genuine. He also said that anybody that wished to email him to ask any questions to feel free to do so. His name is Steve Arrivo and his email address is: steven.arrivo@oxfordbiodynamics.com.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

If you have prostate cancer, it is circulating in your blood. Obviously they are looking there and have the right techniques to find it. Sounds like a good test for those on active surveillance.

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Thanks @bens1, I emailed Steven.

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As I understand it so far (and I might be wrong) "PSE" is a patented approach for combining a regular PSA test with a genetic test for risk markers, to reduce false positives and unnecessary biopsies during routine prostate-cancer screening of the broad population.

I already know I have prostate cancer, so I don't understand how looking for genetic risk markers with every blood test would add anything to the accuracy of my own PSA surveillance, but I might be missing something.

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@jeffmarc

If you have prostate cancer, it is circulating in your blood. Obviously they are looking there and have the right techniques to find it. Sounds like a good test for those on active surveillance.

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My PSA yesterday was < .O1. This January I ll be at the two year mark on ADT. Oct 31st, I ll ask the MO if I can cut the ADT dose in half. FYI only.

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@northoftheborder

As I understand it so far (and I might be wrong) "PSE" is a patented approach for combining a regular PSA test with a genetic test for risk markers, to reduce false positives and unnecessary biopsies during routine prostate-cancer screening of the broad population.

I already know I have prostate cancer, so I don't understand how looking for genetic risk markers with every blood test would add anything to the accuracy of my own PSA surveillance, but I might be missing something.

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I had the same thought….but I remember my urologist telling me that sometimes the surgeon will leave some healthy prostate tissue in place for nerve sparing issues.
That tissue will produce PSA and could point to a false biochemical relapse, thereby calling for salvage treatment which isn’t necessary.
In my case it was the PSA velocity which put me into salvage status but with this new test maybe that could have been avoided??
Guess I’ll never know but I would be in favor of any test which cuts down on excessive treatment and side effects.

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Yes, I'm out of my depth here too, but I'd think that once you've had confirmed prostate cancer — even if it's considered cured now — genetic markers showing that you're more likely to develop prostate cancer no longer add any value to refining the PSA result. You know you can develop prostate cancer because you *have* developed prostate cancer, so your oncologist already knows to take your PSA result seriously.

Again, I might be misunderstanding.

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@ecurb

My PSA yesterday was < .O1. This January I ll be at the two year mark on ADT. Oct 31st, I ll ask the MO if I can cut the ADT dose in half. FYI only.

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Congrats! < 0.01 PSA is a great place to be.

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@ecurb

My PSA yesterday was < .O1. This January I ll be at the two year mark on ADT. Oct 31st, I ll ask the MO if I can cut the ADT dose in half. FYI only.

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At this point, it probably can’t hurt to try it. I know a number of people with advanced prostate cancer, who have cut all drugs and gone for a year or two at least without problems. Monthly tests can protect you if something comes back.

Being < .01 is so much better than being < .1 which is all some see. It sure seems like you are ready for a break with that low a PSA.

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@jeffmarc

At this point, it probably can’t hurt to try it. I know a number of people with advanced prostate cancer, who have cut all drugs and gone for a year or two at least without problems. Monthly tests can protect you if something comes back.

Being < .01 is so much better than being < .1 which is all some see. It sure seems like you are ready for a break with that low a PSA.

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. Need to be reversed

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@ecurb

. Need to be reversed

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Less than/ more than - reverse them. Lol

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