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← Return to Letrazole and Neuropathy
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October 24...late, but experiencing the same. Debilitating pain in joints and muscles, but the worst is the neuropathy in my hands. Excruciating pain. Oncologist said take an aleve with the dose. Did nothing. Next he said to take cymbalta. It's been just a few days on cymbalta and no relief but I read it may take weeks for it to kick in. Now I understand why people give up on this drug. It is vicious and feels so toxic.
Replies to "October 24...late, but experiencing the same. Debilitating pain in joints and muscles, but the worst is..."
Im going to be brave here and say Im troubled your oncologist is telling you to take aleve or cymbalta instead of ADDRESSING the issue. The issue is that some AIs are crippling women! And youre one of many as I was one, too.
The half life of Letrozole is 50 hours.
IMHO, this is whats causing these drastic effects.
Consider asking your oncologist to switch you to exemestane.
Even on exemestane, you might consider a 2 week break
After being on it for 3 months.
If your dr will not consider exemestane for you, say goodbye and find another one.
Frankly, if you switch from letrozole to exemestane, consider taking a week to 10 days break in between dropping letrozole and starting exemestane. Let your body get rid of the letrozole before starting exemestane.
You just might find yourself feeling better and take advantage of it! Get out and enjoy yourself.
If you do this, please let us know how it works out for you.
Remember, WE have choices.
Best to you!
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@jnorki, is the cymbalta helping? Have you discussed switching to a different aromatase inhibitor with your oncologist?