There is a 1 in 8 chance of having breast cancer and 80% of those breast cancers, I have read, are hormonal. The HRT study was skewed toward older women and we older women are well-represented in that 1 in 8. I would be cautious about HRT over a certain age. I know that study is controversial but as a cancer patient with a hormonal cancer, I also want to pass along some caution!