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Good PSA/MRI active surveillance results still require fusion biopsy?

Prostate Cancer | Last Active: Oct 25 2:40pm | Replies (30)
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@pdcar4756

I just heard a lecture from Dr. Klotz at the PCRI conference in September where I believe he said MRI invisible tumors are indolent and of no concern.

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handera | @handera | Oct 25 2:40pm

pdcar4756,
Thanks for your post! Just listened to Dr. Laurence Klotz lecture and the follow-up Q/A (2024 PCRI conference). You can find it at 1:36 - 2:50 in the video here https://pcri.org/2024-conference

Dr. Klotz is one of the "fathers of AS", with 25 years of AS experience. Anyone considering or participating in AS would benefit from this lecture and also the follow-up Q/A.

The fact that PCa tumors, that don't show up on a MRI are indolent, don't metastasis and don't result in PCa specific death is depicted in the attached summary slide.

This Sloan-Kettering study stratified 1449 men who had RP, due to GG2 or greater, based on their MRI PIRADS score according to the observed level of BCR, metastasis, PCa specific mortality and other-cause mortality.
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