Yeah the one thing we all have in common is the many, many ways we have tried to deal with CIC, or IBS, or any other GI malady.

I've been on Motegrity for a year, but have to supplement with Dulcolax which I shouldn't do and - well Dulcolax does what Motegrity is supposed to do. Frustrating. I've tried Linzess and, nothing, nothing at all. Clearly these meds can have drastically different outcomes on different people. Approach all potential solutions with caution!

The best thing we can do is support each other with what we've found to work, and what doesn't work. It's one big game of trial and error. Except it's not a game. Well I'm grateful for you and all the other people who post here.