Hi @marymj7! I don't know when my doctor will order it but I will post when I have a 24-hour urine test to say if there's any impact from Tymlos. I haven't been able to find any information regarding whether Tymlos has caused worsening of pre-existing hypercalciuria that has been controlled. The doctor and everything I can find online say it is a possible side effect of Tymlos (no one can answer how it affects pre-existing hypercalciuria). The hydrochlorothiazide works well for me so I'm hoping it continues to keep my urine calcium down! Good luck - I hope it works for you too!