← Return to Worried about starting Tymlos Wednesday and question about P1NP score

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@windyshores

@jennirdh did your doctor warn you about the strong Prolia rebound, which results in a decrease in bone density and more importantly, increase in fracture risk? Ibandronate (Boniva) is not recommended by sources like Keith MCCormick's "Great Bones" as the best approach to counter that rebound. If you were on Prolia for awhile, Reclast is recommended and if you were on for just 1-3 shots, alendronate (Foasamax) might work. My doctors won't even use Prolia because of this rebound risk. Tymlos will be a good drug after fractures in my experience.

Not trying to cause regret here. Just posting because you mention getting back to Prolia and in consultation with your doctor, maybe you can come up with an alternative to protect your gains.

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Thank you for that info! My endocrinologist’s office had several changes to their nurse practitioner position since I have been a patient there and the rebound effect was not stressed to me, or by my PCP! Time to change for sure. Meanwhile it sounds like Tymlos may be the most effective way to regain some bone (hopefully) fast. I’m only 67 and am so restricted right now in what I can do, even after 2 kyphoplasty procedures. Ugh I watched my mom go through osteoporosis and it sucks!!!