Hello. I don't have heartburn issues. I do have severe arthritis and spondylosis issues (pain) and I can't imagine having increased musculoskeletal pain, which, according to Reclast website, is a common side effect. I take maximum Nsaids daily, which doc didn't ask about, but I saw on the Reclast information that it's best to avoid them. I can't function properly without them. Before someone tells me how bad they are, I skip days and use tylenol but it's not nearly as effective. I just made an appointment with my spine doc to talk about injections and discuss my osteoporosis. Thanks for the reply.