Hi, I also take Duloxetine after Two years ago trying Gap and Lyerica. They were no help, only gained 25 pounds. I lost the weight after a year and my Neuroligist placed me on Duloxetine(30mg) inj Aug of this year...COULD'NT BE HAPPIER. I requested to up the dose to 60 mg. My joints fell much bettewr and the Knumbness is less. I take 10 mg of Anmien for sleep as well.

Good Luck!