kell4042,
some have extreme reactions to Reclast "1%," they say. Some 30% have a miserable flu-like response that lasts for weeks, before resolving gradually. There isn't a good way to know your reaction before the injection.
There isn't a way of ridding your body of the medication. If you are extremely miserable someone can prescribe steroid. But steroid is terrible for you bones.
It is important that you contact the prescribing physician.
" When a special category of phagocytic T-cells, called gamma-delta T-cells, encounter the zoledronic acid, they engulf it, just like an osteoclast will engulf alendronate or zoledronic bound to the bone surface. And just like an osteoclast that engulfs a N_BP undergoes apoptosis (programmed cell death), the gamma-delta T-cells that engulfs a N-BP also undergoes apoptosis. The difference is, when a gamma-delta T-cell undergoes apoptosis, it releases inflammatory cytokines, such as IL-1, IL-6, and TNF-alpha, just like when it encounters a flu virus. And these inflammatory cytokines mediate the temperature rise and myalgias, just as with a flu infection in some patients."
This is how the doctor who ran the clinical trials describes the APR--accute phase rection. He advises he use of tylenol and an allergy med. He also says that a person is unlikely to have this reaction with the second injection. I say a person with this reaction is unlikely to have a second injection.
I'd sooner see you on an anabolic, Tymlos or Forteo. And do you have a diagnosis indicating why you have early osteoporosis. But for now, if you decide to weather these weeks call your prescriber. If you don't have an endocrinologist, you might get a referral. If it is completely unbearable, you can go to emergency where that could give you IV steroid.
I'm sorry you are having this miserable reaction. And I hope it resolves quickly, but let us know.