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Somebody tell me why CKD stage 3a or 3b is no big deal.

Kidney & Bladder | Last Active: Oct 11 3:55pm | Replies (40)
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@windyshores

MY eGFR is stable at around 40. If it drops again I will certainly make an appointment. I did a CT with oral uranium and got really sick, but not necessarily due to kidneys (it wasn't investigate).

Cursory googling would seem to say that a nuclear kidney scan is fine but it may be more complicated than that https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380202/ I need to look into it further.

I have been told the creatinine based eGFR is affected by all kinds of things: hydration (of course), exercise, low blood pressure, low ejection fraction (heart), muscle loss etc. and that the Cystatin C is more stable. But yeah, my true GFR is probably around 45.

I have a 20% dose of Reclast with one hour IV hydration and infusion over one hour. Normal dose is 5mg over 12 minutes I believe. I wish I could still take my NSAID!

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Replies to "MY eGFR is stable at around 40. If it drops again I will certainly make an..."
collegeprof | @collegeprof | Oct 11 1:08pm

@windyshores What nephrologists and their associates look for is consistency. In an ideal world, the 2 tests should come close, but that is not always the case. If you are a Mayo patient, they have a pamphlet on the procedure and Iothalamate dye. The nuclear kidney test is not complicated but it involves drinking water, inserting the dye, and emptying your bladder. If you want accuracy of kidney function, this is the best and safe test for most. It also allows the nephrologist to prepare a patient for dialysis or transplant.

Again, you are correct. There are a lot of variables that go into the Creatinine eGFR test, and for that matter, changes may be inconsistent for quarterly testing. Cystatin C is more stable as you suggest, but stability does not equate to accuracy as this nuclear test does.

Last thing about Nsaids, over time you can expect gastric issues including Crohn's disease. Glad you are off that.

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