Connect
← Return to In praise of Orgovyx
Discussion
Prostate Cancer | Last Active: Oct 17 2:02pm | Replies (39)
Comment receiving replies
Well , after gushing about how great I was doing on Orgovyx after almost 3 months, my PA called yesterday and said my liver enzymes were getting “pretty high”. 50 somethings for 2 of them that commonly rise. I told her I felt great but she wasn’t impressed.
I asked about alternatives and she said there weren’t any - all the ADT drugs had the same side effects and if I had to go off of Orgovyx it would just be radiation.
Has anyone else ever experienced this? I’m thinking they take me off during 5 wks radiation and then put me back on for 3 months? Hardly been on long enough to take a ‘holiday’. Thoughts? Thanks!
Replies to "Well , after gushing about how great I was doing on Orgovyx after almost 3 months,..."
Connect
I was on Orgovyx for 6 months. My testosterone went down to 16 and my PSA became undetectable. The side effects--occasional hot flashes, feeling tired--were very manageable and well worth it. My liver enzymes also increased: both ALT and AST to >100. My Urologist called part way through and suggested coming off Orgovyx because of this. BUT I consulted a liver specialist who assured me it was not a concern to have these increases temporarily. I continued Orgovyx. Now that it's done, my liver functions are back to normal. My treatment is at UCSF and I think the doctors are excellent. Bottom line is that you should consider seeing a liver specialist for advice about liver enzymes.