Hmmm...just read this, today. I'm down to 5mg as of two days ago and have experienced stiffness and soreness in the right wrist, only, has been going on for the last 3 weeks or so. Mine, too, subsides through the day. When I saw him 2 days ago, rheumatologist didn't think it was related to the PMR. Now, I'm not so sure. He ordered X-rays and I see him for a follow up in a week and a half. I was tempted to see my hand specialist to get a cortisone shot in the wrist and I've moved my trackball mouse to the left side (awkward), because mousing with the right hand, puts my right wrist right where the pain is. I'll watch this thread to see others' developments.