Well , after gushing about how great I was doing on Orgovyx after almost 3 months, my PA called yesterday and said my liver enzymes were getting “pretty high”. 50 somethings for 2 of them that commonly rise. I told her I felt great but she wasn’t impressed.
I asked about alternatives and she said there weren’t any - all the ADT drugs had the same side effects and if I had to go off of Orgovyx it would just be radiation.
Has anyone else ever experienced this? I’m thinking they take me off during 5 wks radiation and then put me back on for 3 months? Hardly been on long enough to take a ‘holiday’. Thoughts? Thanks!

How long do you stay on Orgovyx depends on what kind of cancer you have and what your Gleason score is. In my case because of the cancer I have I’ve been on Lupron and then Orgovyx for over seven years.

The NCCN calls for 6 months if a Gleason seven, 18 months for Gleason 9, and 24 months for Gleason 9 or 10.

That can vary, depending on how your cancer started or came back

With early-stage cancer, usually a few months after some other treatment (e.g. surgery, radiation), just to be safe.

With advanced-stage cancer like mine, forever (or until there's some new medical breakthrough).

I suspect many people fall somewhere between these extremes.

I was told today that it depends on the severity of the cancer. Up to 2 years if fast growing version. The PSA count will determine when they take you off of the Orgovyx and that is done by your urologist.