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In praise of Orgovyx

Prostate Cancer | Last Active: Oct 17 2:02pm | Replies (39)

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@northoftheborder

Yes, that's a good point, and my life would have been much simpler if either of those had been an option for me.

The issue with Lupron is that it causes an initial testosterone surge, which wasn't a good idea for me when they'd just detected my cancer by way of a spinal metastatis that was growing rapidly and severly compressing my spine — my future was balanced on a knife edge, so we needed to bring my testosterone down ASAP. In 2021, Firmagon was still the only option in Canada for that (other than surgical castration).

Because Canada's a smaller market than the U.S. or E.U., Pfizer didn't bother starting the approval process for Orgovyx until later. Health Canada signed off on it about a year ago, and I was in the very first group of patients to have access to it earlier this year. My pharmacist hadn't even heard of it yet when I brought in my first prescription.

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Replies to "Yes, that's a good point, and my life would have been much simpler if either of..."

In order to stop the Lupron PSA surge they give you biclutamide for two weeks before Lupron and then you don’t get the surge.

Your doctor should’ve known that, but urologist don’t know all that much compared to some oncologists.