I would recommend taking 1 Claritin or Allegra an hour or two before your shots. I had rashes on my arms after a couple of my shots and since taking Claritan I have not experienced that. Sore arms. Yes. Lasts about two days. Goes away. Best of luck! Please report how it goes for you!

@pami Evenity doesn't cause the fever and fluishiness that Reclast does, so not sure why you would need Tylenol or Motrin right after the injections.

Evenity's peak of action seems to be around 11 days for some of us (you can look this up) and that is when some of us, at least me and my friends, feel side effects.

If you are prone to allergic rashes, Claritin might help or Benadryl if you are not driving!

Be careful not to drink too much water! Again hydration was suggested for Reclast but Evenity is subcutatneous not IV. I once drank too much water for a kidney test and had some symptoms. Salty water or Gatorade is safer if you are going to hydrate a lot but I am not sure it is necessary with Evenity. Maybe others had different experiences though.

I find it ironic that when you called the manufacturer of Evenity to report your possible side effect about ankle and feet pain and they told you it "wasn't a side effect that had even been mentioned". Well, you were mentioning the side effect to them! It sound like they weren't taking your reaction seriously.

@dooshie I guess this comment is too late to help with your first injection but I'll post it anyway.
I think reactions to Evenity are getting over expressed somehow in this group or elsewhere. The immediate reactions are often mild to non-existent. I'm not discounting anyone who has some serious reactions but in general it's pretty mild. My 12 months of injections were without any side effects worth mentioning. I say it that way because I see some listing all their side effects and it may make it seem more serious than it was. Yes, I had a stinging sensation (for 2-5 seconds) once or twice out of 24 injections. Two or three times there was a bit of puffiness at the injection site for two or three hours. Once there was a bruise. Sometimes I got stimulated for a few hours. I say good grief that is all nothing. That's pretty normal for sticking a needle in your skin and injecting something into it. I could have as much reaction to injections of water I suspect.
Again to anyone who has a serious reaction I'm not denying your experience.

BTW, I see people saying they always do all these different meds and techniques to prevent reactions and that because of that they never have reactions. My response is that with Evenity you likely would have had no reactions without those tricks.
So to my mind there is no reason to be taking Tylenol or Claritin or antihistamines or any of the things folks do for Reclast.
@pami I do see in your comment that you figured out ways to stop the reactions you were having and that's great.
In my case I would be just as likely if not more likely to have an unpleasant reaction to Tylenol or Claritin etc as I am to Evenity. Seriously!