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Treatment Decision - Radical Prostatectomy versus Radiation Therapy
Prostate Cancer | Last Active: Oct 19 10:23am | Replies (57)Comment receiving replies
There are clinical trials that have you take one drug, but the second drug you may not get because you are the generic side of the trial. You also won’t have any idea you are taking the generic instead of the real drug.
There have been recent test that have not really looked good for the patient because they don’t give the most effective combination of ingredients.
If you’re considering a trial, come back here and ask about what people think of it
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Yes, a good example of that is the TITAN study for metastatic castrate-sensitive prostate cancer (mCSPC) — there was an experimental group taking ADT + Apalutamide (Erleada) and a control group taking ADT + a placebo.
A couple of years into the study, they realised that the the ADT + Apalutamide combo was so effective at delaying or preventing cancer progression that they had to unblind the study for ethical reasons and offer the placebo group the opportunity to switch over and start getting Apalutamide as well.
https://pubmed.ncbi.nlm.nih.gov/33914595/