1. < Breast Cancer

Genetic testing...does anyone have the CHEK2 gene mutation?

Posted by sandyjr @sandyjr, Sep 17, 2019

I have had bilateral breast cancer. According to my genetic test, I do not have the BRAC1 or BRAC2 mutation...I have the very rare CHEK 2 mutation. Has anyone had this mutation? If so, what was your plan of action?

Interested in more discussions like this? Go to the Breast Cancer Support Group.

Zebra | @californiazebra | Nov 18, 2023
In reply to @deborahmontana "Hi Zebra, I'mm so Sorry and feel beyond stupid for my question and suggestion. YOU QUOTE:..." + (show)
@deborahmontana

Hi Zebra,

I'mm so Sorry and feel beyond stupid for my question and suggestion.

YOU QUOTE:
"I did have genetic testing and I have both the BRCA2 and CHEK2 mutations."
"I not only have a lot of allergies, but am also missing enzymes needed to metabolize a lot of meds. They become toxic in my body."

Thank you for your insight, knowledge and GRACE... Deb

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@deborahmontana
I appreciate all suggestions and that you cared enough to make them. Thank you. 🙂 Zebra

REPLY
mchler73 | @mchler73 | Oct 5 9:44am

My oncologist explained that my Genetic test shows I have CHEK2 Mutation and said it can be linked to breast, colon and prostate cancers.
Anyone else have this?

REPLY
2 replies
Moderator
Colleen Young, Connect Director | @colleenyoung | Oct 5 7:36pm
In reply to @mchler73 "My oncologist explained that my Genetic test shows I have CHEK2 Mutation and said it can..." + (show)
@mchler73

My oncologist explained that my Genetic test shows I have CHEK2 Mutation and said it can be linked to breast, colon and prostate cancers.
Anyone else have this?

Jump to this post

Hi @mchler73, I moved your question about looking for other members who have the CHEK2 mutation to this existing discussion:

- Genetic testing...does anyone have the CHEK2 gene mutation? https://connect.mayoclinic.org/discussion/genetic-testing-does-anyone-have-the-chek2-gene-mutation/

I did this so you can read the previous posts and connect with others who have CHEK2 like @sandyjr @dianamiracle @wwbosworth @dick61 @astaingegerdm @cjs123172 @flowerfarmerforever @deborahmontana @cartersgirl2 and more.

Mchler, will other members of your family also have genetic testing done?

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2 replies
mchler73 | @mchler73 | Oct 5 9:43pm
In reply to @colleenyoung "Hi @mchler73, I moved your question about looking for other members who have the CHEK2 mutation..." + (show)
@colleenyoung

Hi @mchler73, I moved your question about looking for other members who have the CHEK2 mutation to this existing discussion:

- Genetic testing...does anyone have the CHEK2 gene mutation? https://connect.mayoclinic.org/discussion/genetic-testing-does-anyone-have-the-chek2-gene-mutation/

I did this so you can read the previous posts and connect with others who have CHEK2 like @sandyjr @dianamiracle @wwbosworth @dick61 @astaingegerdm @cjs123172 @flowerfarmerforever @deborahmontana @cartersgirl2 and more.

Mchler, will other members of your family also have genetic testing done?

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@colleenyoung
I will probably have my 14 year old son tested.
At this point, I am pretty confused about all of this and not really sure what to think or do.

REPLY
Ingegerd Enscoe, Alumni Mentor | @astaingegerdm | Oct 5 11:30pm

@mchler73
One of my daughters has the CHEK2 mutation. She happened to be part of a study at a free community clinic.
Since then she is monitored twice a year- mammogram and MRI six months apart.
I’m encouraging my other daughter and my son to get tested as well.
I was diagnosed with breast cancer 32 years ago, negative for BRCA mutations. I recently tested negative forCHEK2.

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1 reply
wwbosworth | @wwbosworth | Oct 5 11:37pm
In reply to @colleenyoung "Hi @mchler73, I moved your question about looking for other members who have the CHEK2 mutation..." + (show)
@colleenyoung

Hi @mchler73, I moved your question about looking for other members who have the CHEK2 mutation to this existing discussion:

- Genetic testing...does anyone have the CHEK2 gene mutation? https://connect.mayoclinic.org/discussion/genetic-testing-does-anyone-have-the-chek2-gene-mutation/

I did this so you can read the previous posts and connect with others who have CHEK2 like @sandyjr @dianamiracle @wwbosworth @dick61 @astaingegerdm @cjs123172 @flowerfarmerforever @deborahmontana @cartersgirl2 and more.

Mchler, will other members of your family also have genetic testing done?

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Yup, CHEK2 and Lynch Syndrome MSH6. I’ve played wack-a-mo with my 4 cancers. I advocate for myself and have caught all them at an early stage.

REPLY
2 replies
mchler73 | @mchler73 | Oct 5 11:43pm
In reply to @wwbosworth "Yup, CHEK2 and Lynch Syndrome MSH6. I’ve played wack-a-mo with my 4 cancers. I advocate for..." + (show)
@wwbosworth

Yup, CHEK2 and Lynch Syndrome MSH6. I’ve played wack-a-mo with my 4 cancers. I advocate for myself and have caught all them at an early stage.

Jump to this post

@wwbosworth
What 4 cancers did you have and when?
I am glad you caught them all early!

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1 reply
mchler73 | @mchler73 | Oct 5 11:46pm
In reply to @astaingegerdm "@mchler73 One of my daughters has the CHEK2 mutation. She happened to be part of a..." + (show)
@astaingegerdm

@mchler73
One of my daughters has the CHEK2 mutation. She happened to be part of a study at a free community clinic.
Since then she is monitored twice a year- mammogram and MRI six months apart.
I’m encouraging my other daughter and my son to get tested as well.
I was diagnosed with breast cancer 32 years ago, negative for BRCA mutations. I recently tested negative forCHEK2.

Jump to this post

@astaingegerdm
I was diagnosed with breast cancer last year and alternating mammogram and MRI every 6 months so I guess that’s good if that is what they recommended for your daughter. Thank you.

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wwbosworth | @wwbosworth | Oct 5 11:47pm
In reply to @mchler73 "@wwbosworth What 4 cancers did you have and when? I am glad you caught them all..." + (show)
@mchler73

@wwbosworth
What 4 cancers did you have and when?
I am glad you caught them all early!

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Melanoma, thyroid, endometrial and last March kidney.

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1 reply
wwbosworth | @wwbosworth | Oct 5 11:51pm
In reply to @wwbosworth "Yup, CHEK2 and Lynch Syndrome MSH6. I’ve played wack-a-mo with my 4 cancers. I advocate for..." + (show)
@wwbosworth

Yup, CHEK2 and Lynch Syndrome MSH6. I’ve played wack-a-mo with my 4 cancers. I advocate for myself and have caught all them at an early stage.

Jump to this post

When I first found out that I had two genetic mutations, I read a post from a 74 year old man who had had seven cancers. In a weird way it made me hopeful. I realized that cancer is not a death sentence and we can live a normal life span, which was verified by my oncologist. We do, however, need to be vigilant.

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