Diagnosed at 71, I’m 74 now. My PSA was 4.72, but my Gleason was 8. My RA initially wanted me on Lupron for 12 months - 4+4+4. When I met with him prior to the second shot, he wanted to do a 6 month which I agreed to. Went back to 4 month for the last shot so I was on Lupron for 14 months. PSA still under .25 two years later.

I’m not a doctor, but if one doctor is telling you to be on Lupron for 6 months and the other 18 months, I would split the difference and do something in the 12-14 month range. Also, it takes awhile for the side effects to wear off which is something else to consider.

Hope this helps you with your decision. Good luck.