@lizzabeth I looked Farxiga up: https://www.drugs.com/farxiga.html

Do you have diabetes or heart issues? Do you hydrate well?

An eGFR of 45 doesn't get that much attention from my nephrologist. Mine is lower than that most of the time, down to 36 from 53 in 2022 for unknown reasons. Noone has mentioned any medication for me.

Reclast can affect kidneys of course. I am doing 1 mg instead of the normal 5mg, every three months for a year. My doctor is protecting my kidneys that way as well as listening to me about my sensitivity to meds.

Can you have a Cystatin C GFR done? Some of us have found it to be more reliable and more positive than the usual creatinine based eGFR.