Anyone take carboplatin and doxorubicin for recurrence of ovarian ca?

So glad I was able to help. I had Liposomal DOXOrubicin and carboplantin. The doxil amount remained the same for the 6 infusions. The carbo did change, I think maybe it had to do with my weight? I am 75, 5.4ish" weight is around 130-134, and not Braca positive. Tumor cells were HER2 positive 2+, ER and PR negative. I am not with a recognized cancer group. I receive my care from Mayo in JAX but live hours away from Mayo. I didn't have any nausea with this treatment but did have some from Enhertu. Someone told me to just plan to spend some cozy days in bed when I felt badly. Again, I tried to just walk everyday and keep to a schedule with things like meals and shopping. Definitely keep up a social life when you are feeling up to it. You might find that weeks 3 & 4 are relatively ok. The very best to you teal sister!

Westonan, this was meant to reply to you, couldn’t figure how to fix.
Wow, they loaded me up with so many anti nausea meds and prescriptions, it’s great to hear your experience. I eat a lot of fresh ginger, in my teas and such. Try to stay socially connected, but don’t like sharing this too much, as it can be a focal point. Just hate when I’m having a good time, and the focus turns on this.
Have to ask, did you loose your hair? The doc said some thinning. Then while getting infusion, the nurse said loss by week 3 to 6. Folate, hrd, Er, . So Elahere’s possible, just not sure with visual effects including cateracts.
I’m 5’7” , 120 lbs., like all the good input, keep a limit on internet. And still learning it.
Would it be ok to pm?

@jodimj I did a search and did not find anyone within the Gynecologic Cancers Support Group who has been administered Doxirubcin carboplatin.

I type "Doxirubcin carboplatin" in the Search box at the top of this page and turned up discussions in other Support Groups for other kinds of cancer. You might like to start there. In the meantime, I will do a more thorough search and see if I can turn up anyone else who has been treated with Doxirubcin carboplatin.

Have you already started on Doxirubcin carboplatin?

Can you tell me if this combination or doxorubicin is used at Mayo clinics? I did get some responses, but was told neither Mayo, MSK, and another top hospital do not use this on ovarian cancer. This has me concerned, protocols imaging vary as well. I was told mayo doesn’t use cat or pet scans often for this cancer as well.
I’ve been on this for 4 treatments? .. and numbers are rising, both CA 125 , and natera. Interested to know what others get treated with for recurrence, braca -, some folate.
TIA

Can you tell me if this combination or doxorubicin is used at Mayo clinics? I did get some responses, but was told neither Mayo, MSK, and another top hospital do not use this on ovarian cancer. This has me concerned, protocols imaging vary as well. I was told mayo doesn’t use cat or pet scans often for this cancer as well.
I’ve been on this for 4 treatments? .. and numbers are rising, both CA 125 , and natera. Interested to know what others get treated with for recurrence, braca -, some folate.
TIA

I have had carboplatin and Caelyx in 2022, 2023 and 2024/5. Caelyx is PEGylated liposomal doxorubicin. It lasts in your system for longer than doxorubicin, is not as cardiotoxic and you are able to receive more of the altered drug. Carboplatin side effects are well documented. It mostly just makes me nauseous. Caelyx can ulcerate any soft tissue it comes in contact with. Two weeks after treatment I get mouth ulcers where the upper and lower jaws meet. They can be extremely painful, and I often purée food to make it easier to eat. Soups have been good, because it’s protein as well as fluids. It’s also given me colitis of the large intestine, but I don’t know if the diarrhoea that I get is from that or the Whipples procedure I had in 2021. There are other symptoms but they are fairly minor in comparison, or I have just gotten used to them.
I have had recurrent ovarian cancer since 2010. I am up to my 49th chemo cycle. I have had 8 chemotherapy treatments since 2010. I had a 7th cycle today of Caelyx and carboplatin. That’s because the scans last week showed that the cancer is smaller, but still there. I am an experiment, because of the length of time I have lived, and how much chemotherapy I have already gone through. I hope this helps.

I thought I should add that I have never lost my hair with these drugs, although it does seem to thin out a little. I get night sweats too, but I think that might be the dexamethasone that I take to stop bad reactions for the first few days only.