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How long did your doc have you on Tymlos?
Osteoporosis & Bone Health | Last Active: Oct 6 11:16am | Replies (53)Comment receiving replies
I am trying to learn about these bone turnover markers in blood tests. I see a "C-Telopeptide, Serum" (up to 778 from 590 three months ago), "N-Telopeptide, Urine" (which gives me a NTx of 58, too high), a "Propeptide Type I Collagen" (up to 220 from 191 three months ago). My doctor did these tests, but all he told me was that my Vitamin D is too low, even though the report says the PT1C is too high. Can someone explain these to me? I am postmenopausal, going on 15 years now.
I was completely exhausted and weak on TYMLOS after 6 months. I cut back 5 days ago, as someone here suggested, rather than go cold turkey, as my doctor suggested. I feel so much better! So, what happens on the 50 dose rather than 80 rather? Do you stay on it longer, or do you have to work back to 80?
Thanks!
Replies to "I am trying to learn about these bone turnover markers in blood tests. I see a..."
@susyt did you have your bone turnover markers (CTX and P1NP) tested before you started Tymlos as a baseline? If so, do you mind sharing the numbers?
As you probably know, CTX is a marker for bone resorption (breakdown), and p1np for bone building. They are useful in monitoring treatment progress for an anabolic such as Tymlos, with certain limitations. If your baseline P1Np is within reference range for postmenopausal women, then your two readings of 191 and 220 were very impressive - an indication that Tymlos is working great! If you feel great at 50mcg Tymlos currently, you could gradually increase the dose to reach a maximum dose thats tolerable to you. I suspect the bone density increase with Tymlos is dose dependent and 80mcg is the dose thats marketed to achieve the desired end results. Moreover, the longer you stay on Tymlos (to a max of 18-24 mo), the more bone you will build. This is backed by clinical studies.
Wish you the best!
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@susyt you can make progress on 50mcg but 60 is better if you can manage. Give yourself time to figure out what you can . If 50 is the limit my doc was happy with that.
Tymlos needs a lot of D3. Can you do a megadose of 10,000 units to get it up? As I wrote before my D3 stayed around 50 with 3,000 units a day but I started at 50.