My understanding is that you need a sample of the original biopsy. then all Signatera tests are compared with it. I’ve heard that Medicare covers it but it’s free if the patient doesn’t have Medicare. In Europe the test is 4000 euros each time. It seems to be a test that has to be done regularly for a long time. I haven’t had a test yet because I’m told an oncologist has to order it. I live in Texas but get my treatment in Europe. I don’t have an oncologist in Texas. I contacted an oncology office but was rejected because I’m not a patient. All I’m asking for is a prescription for a non invasive test.