I had C. Diff then got SIBO. Took Vancomysin for 5 weeks for the c.diff and Xifaxan for couple of weeks for the SIBO. I also have microscopic colitis. I’ve had MC for numerous years. It causes chronic diarrhea. I’m now taking Budesonide for it, and it’s been helping. I hope this helps some. Colitis runs in my family.