My neurologist suggested I take ALA with B12. I was already taking them and continue to do so over 2 years later. I still have burning in feet and calves and asked the doctor if I could be having this from being insulin resistant and pre diabetes, and he said yes. Not one doctor addressed my high numbers or asked me to address prediabetes. I've been doing this all on my own researching and studying all the high numbers in my extensive blood work taken Sept 6 and 12th by a holistic doctor. I've had so many health issues none of my doctors even know about from their short and incomplete exams. I'm on the road to my own recovery now.