I am really happy that you found something that worked for you. I have not had normal blood work for at least 16 years (especially my liver enzymes - alt & ast). Finally, I just had blood work done last week and I'm finding my change in diet habits, and doing a lot more physical work outdoors is paying off and really helping my numbers. I had PMR and was on Prednisone for the past 14 months. So, I know the feeling of when something works and you have that "thank God" moment. What a relief, right?

Thanks for sharing. My dad can't take atorvastatin either. It may or may not have contributed to his PMR and even if it didn't it caused him severe fatigue and muscle weakness... He was on the highest approved dose, which may have been the problem, but we're too nervous to try it again. He was prescribed Crestor, but that led to acute liver damage so that's a no-go... We tried fiber and plant sterols, but his GI tract can't seem to handle it, and that's what brought us to the Zetia. I think it's going to be Zetia or bust for us (meaning we'll probably accept the risk of going without medication and do what we can with diet while hoping he continues to recover from PMR and stroke), so I'm hoping he can tolerate it so we can do something to marginally lower his risk of a cardiac event a little more.

His cardiologist is willing to refer him to the specialty lipid clinic where they evaluate for the new biologic cholesterol medications, but they seem to have a pretty high incidence of side effects.

Thanks to @pmrsuzie, I was able to figure out there is some literature to support that 5 mg Zetia can be effective, which is good to know. Guess we can all give it a try and see if it helps.