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Evenity and Bone Markers

Osteoporosis & Bone Health | Last Active: Oct 6 2:20pm | Replies (24)

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@michaellavacot

I have had bone markers taken during Evenity and they followed the trial data pretty well. Attached is a graph showing good detail on an Evenity trial. P1NP is pretty fast moving after a shot and drops pretty quickly so timing on the blood test needs to be taken into account. Also attached are my personal results. My P1NP was back to baseline at the end of treatment but my CTX was still suppressed so I was likely still building bone at the end of treatment.

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Replies to "I have had bone markers taken during Evenity and they followed the trial data pretty well...."

This worries me that my ctx will get too low. It was only 234 at baseline with no meds. P1NP was 39 at baseline no meds. I have had 3 doses: 7/5, 8/5, 9/6. Had labs done 9/23. CTX 193. P1NP 43. I will not have any more doses, but the drug will remain active for another couple of months due to long half life. Do you think my ctx will keep falling? Scares me, especially about ONJ risk

@michaellavacot, How long after Evenity did you start Prolia? On the chart it looks like it was a couple of weeks after your last set of injections. Is that correct? Have you continued with Prolia?