I went on Prolia 4 years ago. I, too, had mild osteoarthritis in my knees, but it was about 6 months later that I had serious, almost crippling issues with them. What worked for me was taking collagen supplements. I started with gummies, went to powder and am currently taking capsules. They all were miraculous for me; I chose the capsules simply for convenience. A few months ago I started having some serious jaw pain, and worried it was the Prolia causing damage. X-rays showed everything was fine, and my dentist said the jaw has a muscle which can decline with age. It took another month for me to remember that I had recently cut my collagen dose in half. After increasing it back to what I had previously taken, the jaw pain disappeared. I turn 70 next week.