Most people don't realize we already had bio-identical hormones before the late Dr. Actress "discovered" them.
My breast tumor was estrogen-fed, so I have to take estrogen suppressors for 10 years. So far so good. At 63, I'm frankly surprised that I had any estrogen to suppress. As far as osteopenia/osteoporosis go, I have the start of osteopenia in my left femur, but it can be reversed at this stage. I was told to do weight bearing exercises for the rest of my life, to counteract the ill effects of suppressed estrogen on the bones. On the flip side, I am getting absurdly buff, but I seriously do not want to risk breaking a hip. It took a full 6 months after treatment ended to have enough energy to go to the Senior Center gym, but I go every day now.