I have been longing to get off the meds for many months. Currently at 3.25mg Prednisone and 'stuck' also tried Methotrexate and couldn't tolerate it. On 300mg Plaquinil which helped me get from 7mg Pred to 3.25mg but doesn't seem to be helping anymore and may be causing dizziness. My GP is now suspecting the Plaquinil might be giving me cardiac side effects...feels like a no win situation sometimes. Is it better to take your chances with the background inflammation or roll the dice on the horrid side effects of medication. I know which way I'm leaning but as a former RN I am very sceptical about traditional medicine.