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@jodimj

Doxirubicin (red devil) carboplatin , for ovarian cancer. Why can’t i find any conversations on this combo?

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@jodimj I did a search and did not find anyone within the Gynecologic Cancers Support Group who has been administered Doxirubcin carboplatin.

I type "Doxirubcin carboplatin" in the Search box at the top of this page and turned up discussions in other Support Groups for other kinds of cancer. You might like to start there. In the meantime, I will do a more thorough search and see if I can turn up anyone else who has been treated with Doxirubcin carboplatin.

Have you already started on Doxirubcin carboplatin?

Good morning, I did have 6 infusions of lipsomal doxorubicin and carboplatin for my first reoccurrence, in 2022. I had almost 3 years of NED after my initial treatment. I was really upset and scared going into this treatment. Although it wasn't fun, it was doable. I tried to go with the flow with it a respond to what I was feeling that day. Also, when I felt up to it, tried to live a normal life and was able to do so many days. Usually after two weeks or so could count on a couple of weeks of normalcy, or what I remembered as being normal:-) I did have fatigue but always took a walk and tried to socialize and played pickleball when I could and when covid wasn't lurking around. What I found was the worst infusion was number 5 but I noticed the amount of carboplatin was increased. I was 73 at the time and retired so easy for me to have a day of just being cozy and reading. But again, was out walking almost every day and doing water aerobics in the pool for exercise and a social life. Around the 5th one, my doctor wanted to add bevacizumab. Unwisely perhaps, I refused and refused avastin after the 6th treatment preferring to rest. I had had an excellent result from this treatment. My tumors, which weren't very big got even smaller and some resolved all together so it was well worth it. Did not loose any hair. At some point, I decided to add cold packs, Suzzi Pads to my hands and feet although I am not sure that these drugs cause neuropathy . Honestly wasn't as bad as I thought, had an excellent result, and if I had to I would go back on it. After a few months of taking nothing, of course my tumors (in my pelvic area) were growing. I was able to get a grant from the drug company to take Enhertu which was not as strong a chemo. Enhertu stabilized the tumors and some got smaller. I was on Enhertu for 13 treatments, and stopped to take a break and because my lungs were developing ground glass. I am now on a break and waiting to start Everolimus which is in pill form, I hope it works for me. Oh, I also kept daily notes. This helped in that after each infusion, when I wasn't feeling well, I would see that by day 8 or whatever, I went out to lunch with friends so it gave me some hope. Hope this helps and my warmest wishes to you.

I am currently receiving Doxorubicin and Carbo.
I have had two infusions so far. My dose had to be lowered after the first dose because my absolute neutrophils became so low. My second infusion was postponed for two weeks because of that.
For me, I felt good for the first two days afterwards. Day three through day five I was really run dow. After that I got back to feeling normal.

Good morning Westonan, yes this helped a great deal. I’ve been sitting on a fence ( not a compfy place to sit) with this. Thay do have a few variations of this drug, it’s Peglated libsomal Doxirubicin, and carbo. Not sure if you had the same. Think i read they increase the dose around 3rd or 4th, i fear it’s going to do more harm than good. And really just want to run😆
I’m 67, and trying to weigh it all out, nice having cognitive back for a minute. Did you notice anything that area?
In the NW , Oregon, and try to stay active as well. Frontline reduced my walks, 3 to 5 and sometimes 10 miles down to a few blocks a day. Chair exercises with the older folks, lol 90s and 100. Still a kid❣️
Icing ankles and wrist is suppose to help with hand and foot syndrome.
So pleased to hear you kept your hair, they said thinning was possible. Then i read from a woman hers thinned 80% ahhhh lol 😝
Just figure I don’t like advertising this chapter of my life anymore, makes people uncomfortable, and affects self esteem.
Can’t tell you how much your response means to me, may take photo to reread when low on faith.
So thanks again, I really hope the everolinus works for you as well. Are you Brca pos? I’m neg ,hrd plus, and folate high.
It’s been growing since may, not on ct, MRI showed two lymph node nodes, one in groin, one near heart. Neither accessible for radiation or biopsy. In the sigmoid as well, so many concerns with constipation, or diarrhea. Oh dear. Elahere is a potential, none of this appealing.
Hope all goes well, you seem to have the right attitude and spirit. Are you with a recognized cancer hospital group?
Thanks again …and yes it helped❣️❣️❣️❣️
Later my friend , Hugs. Me

Yes, my tumors are brca positive.

Westonan, this was meant to reply to you, couldn’t figure how to fix.
Wow, they loaded me up with so many anti nausea meds and prescriptions, it’s great to hear your experience. I eat a lot of fresh ginger, in my teas and such. Try to stay socially connected, but don’t like sharing this too much, as it can be a focal point. Just hate when I’m having a good time, and the focus turns on this.
Have to ask, did you loose your hair? The doc said some thinning. Then while getting infusion, the nurse said loss by week 3 to 6. Folate, hrd, Er, . So Elahere’s possible, just not sure with visual effects including cateracts.
I’m 5’7” , 120 lbs., like all the good input, keep a limit on internet. And still learning it.
Would it be ok to pm?