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Taking Tymlos but Forteo recommended
Osteoporosis & Bone Health | Last Active: Oct 23 9:11am | Replies (27)Comment receiving replies
@drsuefowler
"Each mL contains 2000 mcg abaloparatide and the following inactive ingredients: 5 mg phenol, 5.08 mg sodium acetate trihydrate, 6.38 mg acetic acid, and water for injection. Abaloparatide is a PTHrP(1-34) analog which acts as an agonist at the PTH1 receptor (PTH1R)."
A comparison of sorts of the two drugs is buried in this https://www.dropbox.com/scl/fo/3cw4ss6rwg77qb0geoqab/ADJcZRegctE8u8ClreaEaq4?e=3&preview=Update+on+clinical+uses+of+osteoanabolic+agents+-+John+Bilezikian%2C+MD.ppt&rlkey=4h9kqq49dycjzru5yfpmis3qo&dl=0
pgs 27 to 30 or so.
Sorry about the link. Here is a language dense version https://pubmed.ncbi.nlm.nih.gov/39252668/#:~:text=Cortical%20bone%20is%20a%20tough,curves%20(R%2Dcurve).
Forteo has been an easy pharmaceutical for me. My blood pressure drops 20 points on the systolic. Even thouth my blood pressure is already low, I never feel dizzy or unbalanced. I always take water and salt before, anyway. Oh, I hope you have luck with it.
Replies to "@drsuefowler "Each mL contains 2000 mcg abaloparatide and the following inactive ingredients: 5 mg phenol, 5.08..."
@gently ,
The Santa Fe Bone Symposium article was very helpful in comparing all three anabolics. When do you take your Forteo? My blood pressure runs about 90 over 60, sometimes lower. I have been taking Tymlos before bed so I don't notice the side effects. When I tried the full dose, the side effects, dizziness, headache, nausea, fatigue, lasted all the next day until about dinner time. Now, I rarely notice them during the day, except the fatigue. I have a blood pressure cuff so I will check how the medicine affects B/P. Thanks so much for your help, both you and @windyshores. It is so nice not to feel alone in this!
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@genlty I cannot access that link. I thought cortical porosity was a key to flexibilty, but not strength. I have not seen any studies on this idea or the one you cite, and wish I could read it.
I have noticed that treatment, at least with Evenity and Reclast, has made me stiffer, less able to lift or reach w/out pain. I don't recall this effect with Tymlos. It does make me wonder about bone density vs flexibility.