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Breast Cancer and Neuropathy

Breast Cancer | Last Active: May 1, 2023 | Replies (36)

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I @msovercomer and welcome to the Breast Cancer group on Connect. You'll notice that I moved your message to an existing discussion about breast cancer, anastrazole and neuropathy. I did this so you could meet other members of the group who are talking about this, including @susan24 @elizm @cindylb @jersey @theda and @cautiousoptimism.

Some other members have also talked about stopping anastrozole due to neuropathy and other reasons. Some were able to take another aromatase inhibitor like exemestane or letrozole. You can read more in this discussion:
– Concerned about the side effects of anastrozole http://mayocl.in/2d4tiKL

Have you talked to your oncologist about taking a different AI if the neuropathy improves with stopping anastrozole?

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Replies to "I @msovercomer and welcome to the Breast Cancer group on Connect. You'll notice that I moved..."

The plan post surgery was to take AIs for 5 years. It took 3 months before the side effects really hit me: joint pain and weakness in my hands, fingers and wrists, numbness & tingling, in addition to general fatigue, which persisted. After 6 months, I transitioned to the second AI, hoping for . some improvement. No change, so after being on it for 6 months and continuing to be miserable, I took the last AI, recognizing that everyone’s experience is different. I continued treatment for another 6 months and quit. I am now contending with elevated platelets and a recent diagnosis of Essential Thrombocythemia, which makes me ineligible to take Tamoxifen, because of the elevated risk of clots & strokes. I am now looking at the prospect of taking a Hydroxyurea, which is supposed to be well tolerated. We’ll see.