Prior to the recent PMR episode, during years of Chronic lower back pain, including 3 failed surgeries; I studied Cannabis versus Opioids at a college and online university sites. I chose my strains of Cannabis not for the "High" but by what Terpenes were inclusive and the percentage of which was for what purpose. I discovered at that time the CBD is more present in the Lessor THC strains, but may have changed by now with all the new Hybrids? Since my gift of an Abbott Spinal Stimulator Implant, I have not partaken in use of Cannabis for years now, but was also interested as you, once I endure the Prednisone intake. I will post the study below for your request of info and let you conduct your research for end decision.
Best Wishes

Prednisone and other corticosteroids are inhibitors of the cytochrome P450 enzyme CYP3A, which affects how the liver metabolizes materials. CBD is another potent inhibitor of these enzymes, potentially leading to higher blood levels of prednisone and longer times that the drug spends in the body per dose.

This is why it’s wise to consult your physician before combining CBD with prednisone. Depending on your dose and medical condition, they may recommend taking the medications at different times or avoiding CBD altogether.

There may also be an increased risk of bone fractures if long-term prednisone is paired with heavy cannabis use. The long-term use of corticosteroids has decreased bone density, leading to osteoporosis. Similarly, a 2017 study reported an association between heavy cannabis use, low bone density, and increased fracture risk.