After 4 years am now on prednisone 5 mg am and 4mg pm. I do not think I am getting off.

I do the same thing. Trying to get optimal cortisol levels to keep me going during the day. Seems like some days there are other factors where fatigue dips and legs get wobbly. And I am tappering so depending on that schedule…I think everybody experience is different so I think we have to listen to our bodies. Thanks

Please talk with a pharmacist or doctor about playing with or splitting any dosages. Also read up and become knowledgeable about your body's natural production of steroids and it's daily cycle. Splitting PMR steroid dosage is not common, but can be done. Your doctor can talk you through why and how to best do it, if your situation calls for it. Drugs are different and not all drugs should have a constant level in your blood stream. Mimicking the natural cycle should be the goal. Steroids are hormones, they are very complex not a simple concept and many are tightly tied to each other.