@gently the Medrol pack starts with six 4mg pills, then 5, then 4 etc. So 24mg, 20, 16, and so on....

I seem to remember another pack that started with 60mg (six 10mg pills). It was 60,60, 40,40, 20, 20, 10, 10 5, 5- for 10 days vs the 6 days above,

Ask your doctor or the infusion center what they recommend. Prior to the infusion I was told to just drink water during a phone call with an infusion nurse, they didn't say to take Tylenol or Zyrtec. When filling out paperwork at the infusion center one of the questions was if I had taken any Zyrtec Claritin etc which I hadn't. Afterwards I thought I should have asked why they ask that, but at that time was more focused on the infusion.
Besides some heartburn which has resolved I had no other side effects and feeling great.

Helped me with Evenity as well to quell inflammation and also stop hives. I was able to complete the series with great gains ranging anywhere from 4.6% to 10.4%. And, my spine is normal! Everything else is in mid-osteopenia range and endo says not unusual for 74 years old. We continue by going back to Prolia a couple of years and then Reclast again. Good success so far.

I have severe allergies to fragrance (anaphylaxis). I just want you to know that my allergist told me that I can take 4 Zyrtec a day if I need to. She said it is a very safe medication. You may want to look into that.