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Hot flushes and the vagus nerve

Prostate Cancer | Last Active: Sep 24 4:09pm | Replies (8)

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@josgen

I often wonder why I haven't experienced heavy hot flashes from ADT drugs; first Firmagon now Orgovyx. Is it the phytoestrogens in soy? I consume a lot of organic soy milk and also eat tofu and tempeh.

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Replies to "I often wonder why I haven't experienced heavy hot flashes from ADT drugs; first Firmagon now..."

Possibly, or maybe you're just lucky that your body doesn't react that way.

I've been on ADT (Firmagon, then Orgovyx) and ARSI (Erleada) since 2021. My side-effects are sometimes annoying but usually quite tolerable, and they seem to diminish a little every year. I used to get several hot flushes a day, for example, and now sometimes I go through several days without one.

Other people report the side-effects of ADT to be unbearable, even if they have to be on it for only a few months instead of "forever". We're all made a little differently (I react *very* badly to steriods and opioids, for example, so I avoid them whenever medically safe to do so).