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@gigiv I hear all the time about CoQ10 - along with many other supplements, and tend to let it "go in one ear and out the other." But just this week, I began taking 3 new meds for my heart & cholesterol, and the nurse mentioned that the cardiologist recommends it with these.
Since I also have Bronchiectasis and Asthma, I decided to take a look and see what Mayo says...
https://www.mayoclinic.org/drugs-supplements-coenzyme-q10/art-20362602
Hmm, sounds like a good idea with those new meds, but what about my lungs? Well, with a deep dive into Google Scholar, I can see where the research is headed:
https://journals.sagepub.com/doi/full/10.1177/17534666231208628
So a few things seem to say CoQ10 is good for asthmatic lungs because it has antioxidative and anti-inflammatory properties, especially for people on long-term inhaled corticosteroids. But, there have been no specific measurable studies reported yet.
And a couple of studies say the "ubiquinol" (CoQ2) version is more bio-available than ubiquinone (CoQ10). So another deep dive led to this review of hundreds of studies reported in scientific literature over 20 years:
https://link.springer.com/article/10.1007/s11886-023-01992-6#ref-CR18
Their conclusions? "...In contrast to CoQ10, no CoQH2 study could clearly demonstrate a reduced cardiovascular mortality; (III) the used concentrations are much higher in studies investigating CoQH2.
According to these results, we conclude that based on the medical data available, CoQ10 is the more promising supplement to prevent cardiovascular diseases and to treat patients with heart failure. Further arguments for CoQ10 are the additive effect in combination with selenium [30, 31••] and the reduction of adverse effects of statin therapy by supplementation with CoQ10 [44,45,46]. Additionally, in all clinical trials included in this study, patients proceeded with their previous medication (statins, antihypertensives and others) and no interactions between CoQ10 and medicines could be observed..."
So, after all of this, what do I plan to do? Follow my cardiologist's advice and add a CoQ10+selenium supplement to my diet. I'll probably try 100mg first since I am a small person. And I'll take it with a meal containing some fat or a snack of nuts since it needs fat to be absorbed.
I'll see if it helps my asthma as well.
Replies to "@gigiv I hear all the time about CoQ10 - along with many other supplements, and tend..."
God bless you Sue. You are always such a wealth of information. Irene5
I just looked CoQ10 up to understand if it is a naturally ocurring element in the body..... and so it is. I have been familiar with it for years and did take it some years ago but not recently. I do take selenium at least once a week. I will probably start the CoQ10 again along with the other supplements that I take either daily or at least each once a week. With being older and the bodies systems not as strong as they were years ago in my youth I try to supplement my diet with the supplements in hopes of keeping the immune system strong.
Glad to have had the question asked and Sue's information and answer. Thanks
Barbara
Thank you Sue—- you are a treasure!
I am going to try the combo of CoQ10+selenium, and see if there is an effect on my lung and heart issues.
I’ll be watching for your report.
Thanks Sue.
What about
1) One should not take selenium without talking to doctor if: You have an underactive thyroid (hypothyroidism) You have had skin cancer. You are at risk for skin cancer.
2) CoQ10 might make blood-thinning drugs, such as warfarin (Jantoven), less effective. This could increase the risk of a blood clot.
I spoke to a local cardiologist, a woman, who is taking CoQ10 at 200 mg every other day. That sealed the recommendation for me. So, 100 mg per day is apparently good. Even 200 mg daily. I have read where it restores the reduction in systemic CoQ10 that statin medication reduces, so that sounds good. I've read where CoQ10 also reduces arterial plaque or at least stabilizes the formation rate, Pantothenic acid (B-5) is apparently good for reducing arterial plaque as well, but I've not read any clinical studies that confirms it. My PCP also said he has read no info on B-5 being of benefit. Have you ever gotten a broad CT scan of your chest and torso, from lungs to abdomen to see how your arterial plaque situation looks? I have a little plaque around my aortic valve, my carotid arteries and abdominal arteries, but not worrisome. I'm 77 years old and not a doctor.
Sue, thank you for this helpful and science based information. I am sorry you struggle with asthma and COPD. That is hard.
My son's severe asthma turned out to be non-celiac gluten intolerance. Off gluten/dairy and a couple of other foods, he has no asthma and is well. Unfortunately, this is often missed.
Two types of tests were valuable. One is a blood test for IgG (not allergy IgE) gluten/gliadin. The other is a stool test for IgA gluten/gliadin. (We also did similar testing for dairy and eggs.)
It feels criminal that these tests aren't regularly used on asthma patients. Instead, allergy IgE testing is done. That was not only unhelpful, but misleading for us.
On our long journey we were told that my son's very high IgG gluten/gliadin blood result didn't mean anything - "He didn't have celiac." Here is my thinking: While he may not have had celiac yet, the blood antibodies have significant meaning. It seems so obvious to me that we shouldn't have high levels of these antibodies to food proteins in our blood because high levels of food proteins shouldn't be in our blood. They should have been broken down into amino acids and then absorbed. Why they trigger asthma in some, skin problems or migraines or villi damage or anxiety/agitation/depression, in others, is unclear to me.
Hope you find the root cause and heal. Again, thank you.
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thank you @sueinmn for your detailed answer. I saw some conflicting (it seems to me) info on COPD and coQ10, so that threw me off a little, but maybe I did not understand it correctly. I will investigate further. Please let us know if it helps your asthma.
best wishes of great health!