I’ve read some about BAT (bi-polar androgen therapy). Mostly being researched at John’s Hopkins. At this point, it is only employed in those who have become castration resistant. The idea is that the the cancer has adapted to a very low testosterone environment, in part, by developing many more androgen receptors. So what they do is leave you on ADT, but once a month give you a high dose injection of testosterone. As a result, your testosterone level is on a roller coaster. It goes from near zero to very high then back down to near zero, all in the course of a month. This variation supposedly gums up the cancer’s androgen receptors and can actually kill the cancer. The treatment also results in higher quality of life. The research is still in It’s still early days. I’m not castration resistant, but if i become so in the future, i will take a deeper dive into this possible treatment.