@marjou The nasal spray uses one of the ketamine molecules while the IV infusion uses two so it is possible that the nasal infusion won't work for you but the IV will. I went with the IV since it was available and had better results. If doesn't require a hospital stay. I go to the clinic with a family member so they can drive me home. I go in, get the treatment which lasts about an hour, and go home. The nasal spray, from what I recall reading, also requires you go into the clinic or doctor's office, be treated, and then driven home. There was some talk about having the nasal spray available for home use but the belief was that people would abuse it like Special K.