@lindarent none of these meds have caused cancer. Forteo and Tymlos originally had a black box warning that has since been removed since not a single human has gotten cancer from these drugs. There is still some outdated info on this online but you can check the current drug sites.

Regarding the stroke/heart attack are you referring to Evenity? You have finished, right? The ARCH and FRAME studies showed no difference between Evenity and placebo for cardiovascular risk, and a small but statistically significant difference with alendronate, which may be because that is somewhat protective, according to articles I have read. In any case, I have never heard that Forteo causes stroke or heart attack.

The biggest concerns, I think, in your situation, according to McCormick's book "Great Bones, " Dr. Beb Leder's video on YouTube "Combining and Sequential Approaches to Osteoporosis," and my own endocrinologist are:

1) Forteo will not help with the rebound when you stop Prolia, which can quickly reduce bone density and increase fracture risk. My doc would have you do Reclast (Or if you have only done a few Prolia shots, maybe Fosamax).

2) According to those sources Forteo is not effective after Prolia. Check this with your doctor. Are you seeing an endocrinologist?

@lindarent,
osteoporosis requires continued treatment. The bone strengthening effect of all of the medcations declines when you stop taking them. Prolia is the most devastating to stop--without a following drug you'd be worse off than if you'd never taken it.
We keep changing medications because they all be come less effective at some point during treatment.
Forteo is my favorite of all the medicatons. It isn't suspected of causing stroke, heart attack or cancer.
Though you've only taken one injection of Prolia, it might be good to take a bisphosphonate for several months before Forteo. Prolia prevents the bone from breaking down by stopping cell that break bone down from fully developing. But after you stop Prolia those collected underdeveloped cells mature. They can devastate your bone. So we are advised to take a medication that specifically targets those cells.
Many of us have taken all three medications and will rotate back through them a second time, but only because we are afraid of fracturing.