I understand that — if it ain't broke, why try to fix it? Please don't take anything I write as pressure to change; I'm just sharing my own experience for everyone reading this, in case it's helpful for someone.

In my case, I was comfortable going from Firmagon to Orgovyx because they're both GnRH receptor antagonists, and I knew that I responded well to them, so switching to the same thing in pill form didn't feel like a big risk. I would have been much more nervous changing to a different class of ADT (and probably wouldn't), just like I wouldn't switch from Erleada (Apalutamide) to a different kind of ARSI as long as it's working for me.