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Prostate Cancer | Last Active: Sep 20 7:56pm | Replies (40)

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@robertmizek

Stage 4 recurrent prostate cancer person here with a non-medical thought for your consideration:

You may want to consider switching from Eligard to ORGOVYX. I’ve encountered enough fellow PCa patients that reduced the number and severity of their hot flashes by switching from Eligard to Orgovyx, that I insisted that my doctors order it for me. Overall, my hot flashes are a little more than an annoyance. All of my friends who have been on Eligard had more frequent and severe hot flashes.

Good luck on your journey!

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Replies to "Stage 4 recurrent prostate cancer person here with a non-medical thought for your consideration: You may..."

I switched from Firmagon (Degarelix) to Orgovyx (Relugolix) a few months ago. As the shared "-lix" suffix suggests, they are related — both are GnRH receptor antagonists — but just switching from monthly injections to daily pills has made a huge improvement in my quality of life.

I've never taken a GnRH receptor modulator like Eligard/Lupron (Leuprorelin), so I can't compare there, but yes, I'd *never* want to go back to megadosing big monthly injections unless I had no other medical choice. I'm really surprised at how big a difference it makes spreading it out in smaller, daily doses.

The first 4 months I was on Orgovyx I was getting one or two hot flashes a day maximum. After I was on it for five months I started getting more hot flashes. I’m now getting between five and nine hot flashes a day. I use my Embr Wave device at night and that pretty much keeps the hot flashes down while sleeping. I had to start using the fan and my wave device during the day again.

With the wave device if I don’t hit the button right away when I start feeling the hot flash, then it does build some, so the fan helps. Problem is, you can’t always tell when it’s starting to come on, or I am doing something and I can’t hit the button right away.

I pay nothing for Orgovyx. With my insurance if I get a Lupron shot every six months they charge me $400. Crazy!!